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Electronic cigarettes (CBD electronic cigarettes) include a broader sub-category of products, described as personal atomizers (PV), advanced personal atomizers (APV) or electronic nicotine delivery systems (ENDS). These products have a series of designs. Full characterization of e-cigarette design features is necessary to assess the potential risks and benefits associated with its use.

　　 In October 2013, a systematic literature search was conducted to identify studies related to electronic cigarettes and electronic nicotine delivery systems. Ten reference databases (Web of Knowledge, PubMed, SciFinder, Legacy Tobacco Documents Library, Embase, EBSCOhost, Espacenet, Google Scholar, Google Patent, and US Patent Office) are searched using a set of related search terms used alone or in combination. The search criteria includes the following: "thermal runaway" or "battery fire" or "battery explosion" or "lithium battery explosion" or "electronic nicotine device" or "electronic nicotine delivery system" or "electronic cigarette" or "electronic cigarette" or 'Electronics' and'cigarettes'.

　　 The design of electronic cigarettes is usually similar to the size of traditional cigarettes, and to some extent similar to graphic design. Common components of most e-cigarettes include aerosol generators, flow sensors, batteries, and solution (or e-liquid) storage areas

　　Typical electronic cigarette configuration. This shows a wick/heater as an aerosol generator, gauze saturated with e-liquid, a microprocessor for controlling operation (optional) and an LED for mimicking coal combustion (optional).

　　 Electronic cigarettes are currently classified as disposable or reusable. Disposable devices do not have rechargeable batteries and are usually not rechargeable. They may have light emitting diodes (LEDs). The e-liquid container or box can be separated from the aerosol generator or atomizer; the combined atomizer and ink cartridge are called cartridge atomizers. Electronic cigarettes currently on the market usually have an aerosol generator with a metal or ceramic heating element wound around the core bundle.

　　E-cigarettes can use a variety of materials. They include metals, ceramics, plastics, rubber, fibers and foam. Some of the materials can be aerosolized and may have side effects on health.

　　Although the complexity of electronic cigarettes is different, the following introduces the basic operation of the first generation of electronic cigarettes:

　　 1. The user uses the electronic cigarette, which activates the airflow sensor.

　　 2. The air flow sensor detects the pressure change and prompts the current of the LED and the heating element.

　　 3. The electronic liquid saturates the core by capillary action, and then atomizes by the heating element.

　　 4. Subsequently, the atomized droplets of e-liquid flow into the user's mouth and lungs.

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